Fetal exposure to oral isotretinoin: failure to comply with the Pregnancy Prevention Program.
نویسندگان
چکیده
منابع مشابه
Isotretinoin exposure during pregnancy: a population-based study in The Netherlands
OBJECTIVE To estimate isotretinoin exposure in Dutch pregnant women despite the implemented pregnancy prevention programme (PPP) and second, to analyse the occurrence of adverse fetal or neonatal outcomes in these isotretinoin exposed pregnancies. DESIGN Population-based study. SETTING The Netherlands. PARTICIPANTS A cohort of 203,962 pregnancies with onset between 1 January 1999 and 1 Se...
متن کاملWhat is the chance of a normal pregnancy in a woman whose fetus has been exposed to isotretinoin?
Clinical Question: Recently, one of our patients who was taking isotretinoin became pregnant. This occurred despite appropriate counseling, a negative pregnancy test result before commencing treatment, and use of the combined oral contraceptive pill Microgynon 30 (Schering Health Care, West Sussex, England) (levonorgestrel, 150 μg, ethinylestradiol, 30 μg). The patient did not want to terminate...
متن کاملPregnancy prevention among women taking isotretinoin: failure to comply with the recommendations.
OBJECTIVE To assess whether prescribing physicians advised female patients taking isotretinoin according to pregnancy prevention recommendations, whether women understood those recommendations, and whether women complied with recommendations to prevent pregnancy. DESIGN Cross-sectional study designed to collect patients' self-reported information. Women were interviewed by telephone with a st...
متن کاملOccurrence of pregnancy and pregnancy outcomes during isotretinoin therapy.
BACKGROUND Isotretinoin, a teratogen, is widely used to treat cystic acne. Although the risks of pregnancy during isotretinoin therapy are well recognized, there are doubts about the level of adherence with the pregnancy prevention program in Canada. Our objective was to evaluate the effectiveness of the Canadian pregnancy prevention program in 4 provinces: British Columbia, Saskatchewan, Manit...
متن کاملS.T.E.P.S.: a comprehensive program for controlling and monitoring access to thalidomide.
In July 1998, the US Food and Drug Administration approved the marketing of thalidomide for the treatment of cutaneous manifestations of erythema nodosum leprosum. To ensure that fetal exposure to this teratogenic agent does not occur, the manufacturer has instituted a comprehensive program to control prescribing, dispensing, and use of the drug. This program, known as the System for Thalidomid...
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عنوان ژورنال:
- CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne
دوره 160 12 شماره
صفحات -
تاریخ انتشار 1999